AUTHOR=Pu Jun-fan , Zhou Yan-ling , Deng Min , Wu Jing 

TITLE=Case report: A case of blood culture-negative Bartonella quintana endocarditis: blood mNGS is an efficient method for early diagnosis

JOURNAL=Frontiers in Medicine

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1449637

DOI=10.3389/fmed.2024.1449637

ISSN=2296-858X

ABSTRACT=<p><italic>Bartonella quintana</italic> is one of the main causes of blood culture-negative endocarditis, and routine blood culture and serological methods are difficult to achieve early diagnosis. We report a case of blood culture-negative <italic>Bartonella quintana</italic> endocarditis from southwestern Chongqing. The patient was a 67-year-old male scavenger who presented with heart failure without fever as the main clinical manifestation upon admission. He stated having had contact with stray cats in the past 2 months. The combination of clinical symptoms, echocardiography, and blood mNGS testing confirmed the infection of <italic>Bartonella quintana</italic>.</p>