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REVIEW article
Front. Med.
Sec. Pulmonary Medicine
Volume 11 - 2024 |
doi: 10.3389/fmed.2024.1437731
A Comprehensive Review of Mycoplasma Pneumoniae Infection in Chronic Lung Diseases: Recent Advances in Understanding Asthma, COPD, and Bronchiectasis
Provisionally accepted- 1 Beijing Fengtai Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China
- 2 Beijing Tongzhou District Integrated Traditional Chinese and Modern Medicine, Beijing, China
- 3 Beijing Daxing District Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China
- 4 Shijiazhuang Second Hospital, Shijiazhuang, China
This review summarizes the research progress over the past thirty years on the relationship between Mycoplasma pneumoniae infection and chronic respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. Mycoplasma pneumoniae is a common cause of community-acquired pneumonia, particularly in children and young adults. Key findings from recent studies indicate that M. pneumoniae infection is associated with a higher risk of asthma exacerbations and may contribute to the development of bronchiectasis in susceptible individuals. Additionally, emerging evidence suggests that M. pneumoniae-induced immune dysregulation plays a crucial role in the pathogenesis of chronic lung diseases. This review aims to summarize the current understanding of the potential links between M. pneumoniae pneumonia and various chronic respiratory conditions, including asthma, chronic obstructive pulmonary disease (COPD), and bronchiectasis. We discuss the epidemiological data, pathogenic mechanisms, clinical manifestations, and long-term consequences of M. pneumoniae-related respiratory illnesses. Additionally, we highlight the challenges in diagnosis and treatment, as well as future research directions in this field.
Keywords: Asthma, Lung Diseases, COPD, Pneumonia, Mycoplasma
Received: 24 May 2024; Accepted: 02 Sep 2024.
Copyright: © 2024 Guo, Gu, Tian and Du. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Bo-ying Du, Shijiazhuang Second Hospital, Shijiazhuang, China
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