AUTHOR=Liu Qinqin , Chen Ping , Xin Li , Zhang Jiahao , Jiang Meijie 

TITLE=A rare intestinal mucormycosis caused by Lichtheimia ramosa in a patient with diabetes: a case report

JOURNAL=Frontiers in Medicine

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1435239

DOI=10.3389/fmed.2024.1435239

ISSN=2296-858X

ABSTRACT=<p>Mucormycosis is an aggressive fungal disease. Gastrointestinal mucormycosis is rare, but its clinical symptoms lack specificity and mortality is high. Here, we report a case of intestinal mucormycosis caused by <italic>Lichtheimia ramosa</italic> in a 65-year-old woman with diabetes mellitus. The patient exhibited extensive mucosal tissue damage in the colon, with broad, undivided filamentous fungal hyphae present in the intestinal tissue. Therefore, the patient was suspected to have a filamentous fungal infection. Colonic tissue samples were obtained for fungal culture, and the fungus was identified as <italic>L. ramosa</italic> based on morphology and DNA sequencing. This case highlights the importance of pathologists and microbiologists in identifying pathogenic fungi and the significance of screening for mucormycosis in high-risk patient populations.</p>