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SYSTEMATIC REVIEW article

Front. Med.
Sec. Obstetrics and Gynecology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1432672
This article is part of the Research Topic Reviews in Obstetrics and Gynecology View all 4 articles

Extracorporeal membrane oxygenation in obstetrical patients: a meta-analysis

Provisionally accepted
Sijun Deng Sijun Deng 1Xiaoyan Yang Xiaoyan Yang 1Zhizhong Xie Zhizhong Xie 1Wentao Bian Wentao Bian 2*
  • 1 Hengyang Medical College, University of South China, Hengyang, Hunan Province, China
  • 2 Shaanxi Provincial People's Hospital, Xi'an, Shaanxi Province, China

The final, formatted version of the article will be published soon.

    Background: Obstetrical acute and critically ill patients are a special group of patients clinically, with a high mortality rate. Extracorporeal membrane oxygenation is gradually being used in obstetrical acute and critically ill patients and has shown great advantages.Methods: PubMed, Embase, Web of Science, Chinese CNKI Database, and Cochrane Library databases were systematically searched from the earliest available date to March 15, 2024, to obtain relevant studies on extracorporeal membrane oxygenation in obstetric patients. After literature screening, data were independently extracted and summarized using random effects or fixed effects models, depending on the magnitude of heterogeneity.Results: A total of 38 studies (917 patients) were included. The overall survival rate of critically ill obstetric patients supported by extracorporeal membrane oxygenation is 65% (56%-74%), of which the survival rates of antepartum and postpartum patients are 70% (55%-84%) and 63% (47% -78%), the survival rates of obstetric patients supported by VVECMO and VAECMO were 70% (56%-83%) and 56% (44%-68%) respectively.Conclusions: This article systematically reports the survival rate of critically ill obstetric patients under ECMO support. The survival rate of critically ill obstetric patients receiving ECMO is significantly higher than the survival rate of all patients receiving ECMO support, survival rates were similar for prenatal and postpartum patients, but survival rates for patients supported by VVECMO were significantly higher than those supported by VAECMO. It is necessary to further explore the benefits of ECMO for obstetric patients with different disease types in the future.

    Keywords: Extracorporeal Membrane Oxygenation, Obstetrical patients, Survival Rate, Systematic review, Meta-analysis

    Received: 14 May 2024; Accepted: 06 Sep 2024.

    Copyright: © 2024 Deng, Yang, Xie and Bian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Wentao Bian, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.