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SYSTEMATIC REVIEW article

Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1428431

The effectiveness of transnasal high flow nasal cannula in bronchoscopy under sedation：A systematic review and Meta-analysis

Provisionally accepted
Chen Wei Chen Wei 1Shaoyong Ma Shaoyong Ma 2*Jingwen Wang Jingwen Wang 1Na Yang Na Yang 1*Dandan Wang Dandan Wang 1*Liping Yuan Liping Yuan 3*Yingying Wang Yingying Wang 3*
  • 1 Graduate School, Wannan Medical College, Wuhu, China
  • 2 School of Nursing, Wannan Medical College, Wuhu, Anhui Province, China
  • 3 First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui Province, China

The final, formatted version of the article will be published soon.

    Background:: The objective of this study was to conduct a systematic review and meta-analysis of the clinical application effects of transnasal high flow nasal cannula compared to other conventional modalities for oxygen therapy devices in patients undergoing bronchoscopy.Methods: A comprehensive literature search was conducted in multiple English databases, including PubMed, Web of Science, and Cochrane Library, to collect relevant studies on the application of high flow nasal cannula in patients undergoing bronchoscopy ， and conducted a meta-analysis utilizing RevMan 5.4 software, following the predetermined inclusion and exclusion criteria.Results: A total of 12 studies meeting the inclusion criteria were included, involving 1631 patients (HFNC group: n = 811, other oxygen therapy group: n = 820). The meta-analysis results demonstrated that HFNC significantly reduced the incidence of hypoxemia and improved the minimum oxygen saturation compared to conventional oxygen therapy (RR = 0.27, 95% CI: 0.18-0.41, P < 0.00001; MD = 6.09, 95% CI: 3.73-8.45, P < 0.00001). Furthermore, HFNC showed statistically significant differences when compared to non-invasive ventilation in terms of hypoxemia incidence (RR = 3.52, 95% CI: 1.13-10.97, P = 0.03) and minimum oxygen saturation (MD = -1.97, 95%

    Keywords: High flow nasal cannula, Conventional oxygen therapy, Non-invasive ventilation Bronchoscopy, hypoxemia, Meta-analysis

    Received: 06 May 2024; Accepted: 01 Jul 2024.

    Copyright: © 2024 Wei, Ma, Wang, Yang, Wang, Yuan and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Shaoyong Ma, School of Nursing, Wannan Medical College, Wuhu, 241002, Anhui Province, China
    Na Yang, Graduate School, Wannan Medical College, Wuhu, China
    Dandan Wang, Graduate School, Wannan Medical College, Wuhu, China
    Liping Yuan, First Affiliated Hospital of Wannan Medical College, Wuhu, 241001, Anhui Province, China
    Yingying Wang, First Affiliated Hospital of Wannan Medical College, Wuhu, 241001, Anhui Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.