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CASE REPORT article

Front. Med.
Sec. Infectious Diseases: Pathogenesis and Therapy
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1419356

Case report: Thoracic vertebral abscess caused by Salmonella via diagnosed next-generation sequencing

Provisionally accepted
Cao Xiaoguang Cao Xiaoguang 1Xi j. Ni Xi j. Ni 2Chong J. Huang Chong J. Huang 3*
  • 1 Anhui Provincial Hospital, Hefei, China
  • 2 Third People's Hospital of Hefei, Hefei, China
  • 3 Suzhou Hospital of Anhui Medical University, Suzhou, Liaoning Province, China

The final, formatted version of the article will be published soon.

    The genus Salmonella consists of Gram-negative bacteria with various serotypes.It commonly causes bacterial infections that affect the intestines. Infection can occur in humans and animals through the ingestion of contaminated food or water, or through contact with infected animals or environments. Complications commonly include intestinal hemorrhage and perforation, though vertebral osteomyelitis is rarely observed. Therefore, in patients with spinal cord abscesses, The genus Salmonella is typically not considered a likely pathogen, especially in the absence of typical symptoms. In this case, the limited information provided by traditional cultivation methods, particularly under the influence of antibiotics. However, next-generation sequencing (NGS) unexpectedly detected Salmonella, which assisted in formulating the final treatment plan. This underscores the role and clinical value of NGS in pathogen identification.

    Keywords: Thoracic vertebra, Salmonella typhi, NGS, Infection, diagnosis, Case presentation

    Received: 18 Apr 2024; Accepted: 31 Jul 2024.

    Copyright: © 2024 Xiaoguang, Ni and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Chong J. Huang, Suzhou Hospital of Anhui Medical University, Suzhou, Liaoning Province, China

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