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ORIGINAL RESEARCH article

Front. Med.
Sec. Pulmonary Medicine
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1417783

Trends, Prevalence, and Determinants of Unfavorable Tuberculosis Treatment Outcomes Among Adult Patients in Northeast Ethiopia: The Race to Achieve a 90% Treatment Success Rate by 2025

Provisionally accepted
Tegene A. Kitaw Tegene A. Kitaw *Amsalu Baylie Amsalu Baylie Ribka N. Haile Ribka N. Haile
  • Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia

The final, formatted version of the article will be published soon.

    Background: Tuberculosis remains a pressing public health issue, particularly in developing countries such as Ethiopia. The country has set ambitious targets, aiming to achieve a 90% treatment success rate for tuberculosis by 2025. However, there is a notable lack of current data on the region. Thus, recent data on treatment outcomes and their determinants are essential for guiding early interventions and aligning efforts with both national goals and the End TB Strategy. Understanding the current landscape of tuberculosis treatment outcomes and the factors influencing them is crucial for implementing targeted interventions and ultimately gauging how close we are to achieving the set targets.A four-year retrospective study (2019-2022) was conducted among 312 adult confirmed tuberculosis patients. The data were collected using a structured checklist. Analysis was performed using STATA version 18. A Mann-Kendall trend test was conducted to evaluate the significant trends in TB incidence. Multicollinearity was assessed using variance inflation factors (VIFs). A logistic regression model was computed to identify significant determinants with dependent variables. Variables with a p value ≤0.05 in the multivariate analysis were considered to be significantly different.In this study, 84.94% of participants achieved a favorable treatment outcome, with 15.06% experiencing an unfavorable outcome. There was a significant decreasing trend (Kendall's tau (τ) = -0.0686, p-value = 0.021) in unfavorable outcomes, from 18.84% in 2019

    Keywords: Tuberculosis, treatment outcome, determinants, Northeast Ethiopia, trend

    Received: 15 Apr 2024; Accepted: 11 Oct 2024.

    Copyright: © 2024 Kitaw, Baylie and Haile. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Tegene A. Kitaw, Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.