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CASE REPORT article

Front. Med.
Sec. Ophthalmology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1409074

FEVR combined with macular heterotopia in children presenting as pseudo-extropia: A case report and literature review

Provisionally accepted
Yujie Zhang Yujie Zhang Shuimiao Chen Shuimiao Chen *Yanghui Xiu Yanghui Xiu *
  • Eye Center, Xiamen University, Xiamen, China

The final, formatted version of the article will be published soon.

    Familial exudative retinopathy (FEVR) is a hereditary disease involving abnormal retinal vascular development in which macular heterotopia (MH) caused by mechanical-like pulling of the vitreous may lead to pseudo-strabismus. We describe the case of a 12-year-old male patient from China who presented to our hospital with a request for surgical correction of exotropia. Examination revealed that the strabismic appearance was due to MH, and dilated pupil examination of the peripheral fundus revealed that the blood vessels of the left eye and the macula were displaced toward the temporal retina by pulling, and further FFA examination was performed to diagnose FEVR. With good binocular vision and stereoscopic distance vision, corrective surgery for strabismus in this patient would have resulted in a hard-to-resolve diplopia. Therefore, it is important to identify FEVR combined with MH in clinical practice to avoid wrong diagnostic and treatment options.

    Keywords: Familial exudative vitreoretinopathy, Macular heterotopia, pseudo-strabismus, binocular vision, macular perfusion density evaluation

    Received: 29 Mar 2024; Accepted: 08 Aug 2024.

    Copyright: © 2024 Zhang, Chen and Xiu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Shuimiao Chen, Eye Center, Xiamen University, Xiamen, China
    Yanghui Xiu, Eye Center, Xiamen University, Xiamen, China

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