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ORIGINAL RESEARCH article

Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1408342

Relationship between intraoperative hypothermia and hyperthermia with postoperative pneumonia and surgical site infection in major non-cardiac surgery

Provisionally accepted
Qian-Yun Pang Qian-Yun Pang Ya-Jun Yang Ya-Jun Yang Yu-Mei Feng Yu-Mei Feng Shu-Fang Sun Shu-Fang Sun Hongliang Liu Hongliang Liu *
  • Department of Surgery and Anesthesiology, Cancer Hospital, Chongqing University, Chongqing, China

The final, formatted version of the article will be published soon.

    Background: Surgical patients often experience intraoperative hypothermia or hyperthermia, but its relationship with postoperative pneumonia (PPI) and surgical site infection (SSI) is unclear. Here, we conduct a retrospective cohort study to address these issues .Methods: Adult patients undergoing major non-cardiac surgery under general anesthesia were recruited for eligibility. Three indices of core body temperature under hypothermia (<36 0 C) or hyperthermia (>37.3 0 C) were calculated: absolute value ( 0 C), duration of exposure (min), and AUC (area under the curve, 0 C×min). The outcomes were in-hospital PPI and SSI. The risk-adjusted association between intraoperative hypothermia or hyperthermia and PPI or SSI was determined.The absolute value (nadir value of hypothermia or peak value of hyperthermia) was not associated with PPI or SSI. PPI was associated with 1) duration: hypothermia >90 min (OR:1.425, 95%CI:1.131-1.796),

    Keywords: Hypothermia, hyperthermia, pulmonary infection, Surgical site infection, major non-cardiac surgery

    Received: 28 Mar 2024; Accepted: 22 Jul 2024.

    Copyright: © 2024 Pang, Yang, Feng, Sun and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Hongliang Liu, Department of Surgery and Anesthesiology, Cancer Hospital, Chongqing University, Chongqing, 400030, China

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