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ORIGINAL RESEARCH article

Front. Med.
Sec. Obstetrics and Gynecology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1407034
This article is part of the Research Topic Suicidal behavior and depression among perinatal women: Research, Prevention, Intervention and Treatment View all 9 articles

The Incidence and Risk Factors of Depression Across Six Time Points in the Perinatal Period: A Prospective Study in China

Provisionally accepted
Jue Zhu Jue Zhu 1Youchun Ye Youchun Ye 2*Xuan Liu Xuan Liu 3*Yichen Chen Yichen Chen 1Lu Chen Lu Chen 1*Yi Lin Yi Lin 1*Qiming Wang Qiming Wang 1*Jing Zhang Jing Zhang 1*
  • 1 Ningbo Women and Children's Hospital, Ningbo, China
  • 2 Ningbo Yinzhou People's Hospital, Ningbo, Zhejiang Province, China
  • 3 Ningbo Institute of Technology, Zhejiang University, Hangzhou, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    Perinatal depression (PND) affects approximately 15-20% of women. This study aimed to determine the incidence of PND and identify risk factors. A prospective study was conducted at the Affiliated People’s Hospital of Ningbo University. The Edinburgh Postnatal Depression Scale (EPDS) was used to screen for perinatal depression. Classification models were constructed using Extreme Gradient Boosting (XGBoost), Logistic Regression (LR), Random Forest (RF), and Support Vector Machine (SVM), and the optimal model was selected. Between March 2019 to August 2021, a total of 485 participants completed all valid questionnaires. Depression was observed in 75 (15.5%), 47 (9.7%), 25 (5.2%), 94 (19.4%), 85 (17.5%), and 43 (8.9%) cases during the first trimester, the second trimester, the third trimester, 1 week postpartum, 6 months postpartum, and 12 months postpartum, respectively. During the prenatal period, factors such as monthly income, employment status, marital status, and thyroid function significantly impacted depression. Additionally, factors including monthly income, employment status, marital status, parity, and unintended pregnancy were found to affect the likelihood of developing postpartum depression. XGBoost was chosen for its accuracy (0.9097) and precision (0.9005) in predicting prenatal depression, as well as for its accuracy (0.9253) and precision (0.9523) in predicting postpartum depression. In conclusion, the incidence of depression varies throughout the perinatal period, with different factors influencing prenatal and postpartum depression.

    Keywords: Perinatal depression, Incidence, Risk factors, 6 time points, Edinburgh Postnatal Depression Scale

    Received: 26 Mar 2024; Accepted: 01 Aug 2024.

    Copyright: © 2024 Zhu, Ye, Liu, Chen, Chen, Lin, Wang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Youchun Ye, Ningbo Yinzhou People's Hospital, Ningbo, Zhejiang Province, China
    Xuan Liu, Ningbo Institute of Technology, Zhejiang University, Hangzhou, 315000, Zhejiang Province, China
    Lu Chen, Ningbo Women and Children's Hospital, Ningbo, China
    Yi Lin, Ningbo Women and Children's Hospital, Ningbo, China
    Qiming Wang, Ningbo Women and Children's Hospital, Ningbo, China
    Jing Zhang, Ningbo Women and Children's Hospital, Ningbo, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.