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ORIGINAL RESEARCH article

Front. Med.
Sec. Intensive Care Medicine and Anesthesiology
Volume 11 - 2024 | doi: 10.3389/fmed.2024.1382724

Comparison of Sevoflurane and Propofol in Combination with Remifentanil on the Quality of Postoperative Recovery in Patients Undergoing Laparoscopic Bariatric

Provisionally accepted
Zhuolin Shu Zhuolin Shu Tiancheng Lin Tiancheng Lin Dingchen Xu Dingchen Xu Shuyuan Zheng Shuyuan Zheng *
  • Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, Shanghai Municipality, China

The final, formatted version of the article will be published soon.

    Objective: This study aimed to evaluate and compare the effects of sevoflurane + remifentanil (Sev+Rem) and propofol + remifentanil (Pro+Rem) on the postoperative recovery quality of patients undergoing laparoscopic bariatric surgery to determine which anesthesia regimen provides a better overall recovery experience. Methods: Sixty patients were divided into two groups based on the treatments they underwent: Sev+Rem (n = 30) and Pro+Rem (n = 30). The Sev+Rem group received sevoflurane inhalation (0.5%, increasing to 0.5–4%) and remifentanil via target-controlled infusion. The Pro+Rem group received propofol (4–8 mg/(kg·h)) and remifentanil via target-controlled infusion. Anesthesia depth was maintained at a bispectral index of 40–60 in both groups. Perioperative data, hemodynamic parameters, and postoperative recovery quality were assessed. Results: Compared to the Pro+Rem group, the dose of remifentanil in the Sev+Rem group was significantly lower (1693.67 ± 331.75 vs 2959 ± 359.77, P < 0.001), the proportion of patients used norepinephrine was markedly higher [16 (53.33) vs 8 (26.67), P = 0.035], and the time of extubation was earlier (356.33 ± 63.17 vs 400.3 ± 50.11, P = 0.004). The Hemodynamic results showed the HR in the Sev+Rem group was faster than that in the Pro + Rem group at the beginning of surgery and 1 h post-surgery (67.37 ± 4.40 vs 64.33 ± 4.44, P = 0.010; 69.07 ± 4.23 vs 66.40 ± 5.03, P = 0.030). In regard to the assessment of postoperative recovery quality, the emotional state scores in the Sev+Rem group were significantly lower than the Pro+Rem group (36.83 ± 2.79 vs 39.50 ± 4.64, P = 0.009). Conclusion: The two anesthesia modalities (Sev+Rem and Pro+Rem) have their advantages and disadvantages for patients undergoing laparoscopic bariatric surgery and have comparable effects on postoperative recovery quality.

    Keywords: sevoflurane, Propofol, remifentanil, Laparoscopic bariatric surgery, quality of recovery sevoflurane, postoperative recovery quality

    Received: 06 Feb 2024; Accepted: 28 Jun 2024.

    Copyright: © 2024 Shu, Lin, Xu and Zheng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Shuyuan Zheng, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, 200233, Shanghai Municipality, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.