AUTHOR=Zhao Benqi , Ji Yicong , Xu Yangyang , Su Wei , Si Shancheng 

TITLE=Morphological and functional abnormalities of ophthalmic artery in patients with ophthalmic vascular accidents

JOURNAL=Frontiers in Medicine

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1334455

DOI=10.3389/fmed.2024.1334455

ISSN=2296-858X

ABSTRACT=<sec id="sec1"><title>Background</title><p>By observing and comparing the morphological and functional differences of the ophthalmic artery (OA) in patients with ocular vascular accidents (OVAs) due to iatrogenic embolism or non-iatrogenic occlusion, we propose a classification system based on the characteristics of OA on invasive digital subtraction angiography (DSA).</p></sec><sec id="sec2"><title>Methods</title><p>All patients undergoing ophthalmic arterial DSA within 1 week after the OVAs between January 2017 and December 2021 were enrolled and divided into different types, and the differences between iatrogenic embolism and non-iatrogenic occlusion categories were compared.</p></sec><sec id="sec3"><title>Results</title><p>A total of 27 eyes of 27 patients were included in this study. Based on the results of carotid/intracranial arterial DSA, the morphological and functional abnormalities of OA with OVAs can be divided into five types. The proportion of males (7.14%), ocular ischemic syndrome (OIS) (0.00%) and neovascular glaucoma (NVG) (0.00%) in the iatrogenic embolism category was significantly lower than that (84.62, 61.54, and 69.23%, respectively) of the non-iatrogenic occlusion category (<italic>p</italic> &lt; 0.001, <italic>p</italic> = 0.001, <italic>p</italic> &lt; 0.001, respectively). However, the proportion of no light perception (NLP) (100%), anterior segment ischemia (ASI) (71.43%), and orbital involvement (ophthalmoplegia and ptosis, 42.86%) eventually occurring in the former was significantly greater than that in the latter (23.08, 0.00, 0.00%, respectively) (<italic>p</italic> &lt; 0.001, <italic>p</italic> &lt; 0.001, <italic>p</italic> = 0.010, respectively).</p></sec><sec id="sec4"><title>Conclusion</title><p>Ocular vascular accidents can be divided into five types based on the characteristics of OA on DSA.</p></sec>