AUTHOR=Liu Shulin , Shui Li , Liu Zhaohui , Li Qi 

TITLE=Application of articaine in endoscopic endonasal dacryocystorhinostomy: a retrospective study

JOURNAL=Frontiers in Medicine

VOLUME=11

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1332793

DOI=10.3389/fmed.2024.1332793

ISSN=2296-858X

ABSTRACT=<sec id="sec1"><title>Background</title><p>To investigate the comparative effects of local anesthesia using lidocaine with adrenaline vs. articaine with adrenaline in endoscopic endonasal dacryocystorhinostomy (EN-DCR).</p></sec><sec id="sec2"><title>Methods</title><p>This retrospective study included a total of 180 patients. These patients were categorized into two groups: the lidocaine group, which received 2% lidocaine (1:100,000 adrenaline), and the articaine group, which received 4% articaine (1:100,000 adrenaline) for local anesthesia. The study compared anesthesia efficacy, intraoperative pain levels, intraoperative bleeding, as well as differences in heart rate and blood pressure between the two groups.</p></sec><sec id="sec3"><title>Results</title><p>The articaine group demonstrated a significantly lower visual analog scale (VAS) pain score when compared to the lidocaine group, measuring at 4.4 ± 0.6 cm vs. 5.0 ± 1.0 cm, respectively (<italic>P</italic> &lt; 0.0001). Additionally, the articaine group exhibited a higher anesthesia efficacy compared to the lidocaine group (89.0% vs. 76.6%, <italic>p</italic> = 0.0487). Notably, the articaine group experienced less nasal mucosal bleeding during the surgery in contrast to the lidocaine group (<italic>p</italic> = 0.004). However, there were no statistically significant differences in changes in blood pressure and heart rate between the two groups (<italic>p</italic> &gt; 0.05).</p></sec><sec id="sec4"><title>Conclusion</title><p>This study demonstrated that 4% articaine (1:100,000 adrenaline) has superior clinical effectiveness in comparison to 2% lidocaine (1:100,000 adrenaline) in EN-DCR.</p></sec>