AUTHOR=Huang Zhiqian , Qi Jiao , Cheng Kaiwen , Liu Shuyu , Zhang Keke , Du Yu , Lu Yi , Zhu Xiangjia 

TITLE=The relationships between lens diameter and ocular biometric parameters: an ultrasound biomicroscopy-based study

JOURNAL=Frontiers in Medicine

VOLUME=10

YEAR=2024

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1306276

DOI=10.3389/fmed.2023.1306276

ISSN=2296-858X

ABSTRACT=<sec id="sec1"><title>Purpose</title><p>This study aims to explore the relationships between lens diameter (LD) measured with ultrasound biomicroscopy (UBM) and ocular biometric parameters.</p></sec><sec id="sec2"><title>Methods</title><p>Ocular biometric parameters including axial length (AL), white-to-white distance (WTW), anterior chamber depth (ACD), lens thickness (LT) and anterior segment length (ASL) were measured with IOL-Master 700, and the direct measurement of LD was conducted through UBM (ArcScan Insight 100). Relationships between LD and ocular biometric parameters were then investigated. Eyes with AL ≥ 28 mm were defined as eyes with extreme myopia, and eyes with AL &lt; 28 mm were defined as eyes without extreme myopia.</p></sec><sec id="sec3"><title>Results</title><p>A total of 194 eyes from 194 subjects were included. The mean LD was 9.58 ± 0.49 mm, ranging from 8.60 to 10.96 mm. According to univariate analysis, larger LD was associated with elder age, male gender, larger WTW, ACD and ASL (all <italic>p</italic> &lt; 0.05). Meanwhile, the LD was positively correlated with AL in eyes without extreme myopia (p &lt; 0.05), but not in eyes with extreme myopia (<italic>p</italic> &gt; 0.05). Backward stepwise regressions revealed that a larger LD was associated with larger WTW, ASL and AL in eyes without extreme myopia (all <italic>p</italic> &lt; 0.05), while ASL was the only significant variable in eyes with extreme myopia (p &lt; 0.05).</p></sec><sec id="sec4"><title>Conclusion</title><p>Larger WTW, ASL and AL in eyes without extreme myopia, as well as longer ASL in eyes with extreme myopia indicated a larger LD, which provides guidance in personalized surgical choice and promises ideal visual outcomes.</p></sec>