AUTHOR=Yu Xiao , Li Zhao , Yang Xinbo , Wang Xiaopei , Nan Di , Lu Wanhong , Lv Jing , Ma Ying 

TITLE=Microbacterium spp. peritonitis in patients undergoing peritoneal dialysis: a single-center experience and literature review

JOURNAL=Frontiers in Medicine

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1297296

DOI=10.3389/fmed.2023.1297296

ISSN=2296-858X

ABSTRACT=<sec><title>Introduction</title><p>Peritoneal dialysis-related peritonitis (PDRP) caused by <italic>Microbacterium spp</italic>. is very rare, with only 9 cases reported to date. In this study, we report the treatment experiences of 7 patients at our peritoneal dialysis center.</p></sec><sec><title>Methods</title><p>We retrospectively collected clinical characteristics and antibiotic management of all 7 episodes of PDRP caused by <italic>Microbacterium spp</italic>. in 7 patients from at our center over 4 years, and reviewed the documented <italic>Microbacterium spp</italic>. PDRP in the literature.</p></sec><sec><title>Results</title><p>Empiric antibiotic therapy was initiated as soon as possible, and consisted of intraperitoneal (IP) gentamicin in combination with vancomycin. After up to 5 days, gentamicin was changed to meropenem if the treatment was not effective. The intended course of antibiotic treatment was 21-day. Totally, 6 episodes were cured (85.7%), which was higher than reported.</p></sec><sec><title>Conclusion</title><p>The 21-day antibiotic therapy program by combining vancomycin and meropenem may benefit the management of <italic>Microbacterium spp</italic>. PDRP.</p></sec>