AUTHOR=Zhang Yingmiao , Li Kun , Zhan Yu , Shi Lifeng , Zeng Yi , Wang Hui , Lu Zhongxin 

TITLE=Bacteremia caused by Comamonas kerstersii in a patient with acute perforated appendicitis and localized peritonitis: case report and literature review

JOURNAL=Frontiers in Medicine

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1283769

DOI=10.3389/fmed.2023.1283769

ISSN=2296-858X

ABSTRACT=<p><italic>Comamonas kerstersii</italic> (<italic>C. kerstersii</italic>) is a Gram-negative bacterium that was initially thought to be non-pathogenic to humans and is abundant in the environment. In recent years, with the availability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) that enable fast and accurate bacterial identification, there have been increasing number of reports of human infections caused by <italic>C. kerstersii</italic>, indicating that this organism has emerged as human pathogen. In fact, most clinical isolates of <italic>C. kerstersii</italic> are recovered from peritoneal liquid, and bacteremia has been infrequently reported. Here, we report a case of bacteremia caused by <italic>C. kerstersii</italic> in a 28-year-old male patient with acute perforated appendicitis and localized peritonitis and present a comprehensive review of <italic>C. kerstersii</italic> infections in pathogenic diagnosis and clinical treatment as well as prognosis, thus providing a better understanding of <italic>C. kerstersii</italic>-related infections.</p>