AUTHOR=Mahyoub Mueataz A. , Elhoumed Mohamed , Maqul Abdulfatah Hassan , Almezgagi Maged , Abbas Mustafa , Jiao Yang , Wang Jinhai , Alnaggar Mohammed , Zhao Ping , He Shuixiang TITLE=Fatty infiltration of the pancreas: a systematic concept analysis JOURNAL=Frontiers in Medicine VOLUME=10 YEAR=2023 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1227188 DOI=10.3389/fmed.2023.1227188 ISSN=2296-858X ABSTRACT=

Fatty infiltration of the pancreas (FIP) has been recognized for nearly a century, yet many aspects of this condition remain unclear. Regular literature reviews on the diagnosis, consequences, and management of FIP are crucial. This review article highlights the various disorders for which FIP has been established as a risk factor, including type 2 diabetes mellitus (T2DM), pancreatitis, pancreatic fistula (PF), metabolic syndrome (MS), polycystic ovary syndrome (PCOS), and pancreatic duct adenocarcinoma (PDAC), as well as the new investigation tools. Given the interdisciplinary nature of FIP research, a broad range of healthcare specialists are involved. This review article covers key aspects of FIP, including nomenclature and definition of pancreatic fat infiltration, history and epidemiology, etiology and pathophysiology, clinical presentation and diagnosis, clinical consequences, and treatment. This review is presented in a detailed narrative format for accessibility to clinicians and medical students.