AUTHOR=Yuan Ying , Liu Xiaoyuan , Zhou Li , Ding Wuchun , Zhang Liying , Zheng Jinhua 

TITLE=Case report: A case of acute postoperative endophthalmitis following penetrating keratoplasty due to carbapenem-resistant Klebsiella Pneumoniae and literature review

JOURNAL=Frontiers in Medicine

VOLUME=10

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.1110411

DOI=10.3389/fmed.2023.1110411

ISSN=2296-858X

ABSTRACT=<p>A 22-year-old lady underwent penetrating keratoplasty for serious keratoconus. The following day, it was complicated by the development of infectious endophthalmitis. The source of infection was identified as carbapenem-resistant <italic>Klebsiella pneumoniae</italic>. The donor corneal button might be playing a role in infection transmission due to carbapenem-resistant <italic>Klebsiella pneumoniae</italic> in a sputum culture when the donor was still alive. Nosocomial infections were typically severe, rapidly progressive, and difficult to treat. Finally, the patient underwent therapeutic penetrating keratoplasty again with complete resolution of the infection.</p>