AUTHOR=Asanad Samuel , Bayomi May , Brown Douglas , Buzzard Joshua , Lai Eric , Ling Carlthan , Miglani Trisha , Mohammed Taariq , Tsai Joby , Uddin Olivia , Singman Eric 

TITLE=Ehlers-Danlos syndromes and their manifestations in the visual system

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.996458

DOI=10.3389/fmed.2022.996458

ISSN=2296-858X

ABSTRACT=<p>Ehlers-Danlos syndrome (EDS) is a rare, genetically variable, heterogenous group of (currently recognized) thirteen connective tissue disorders characterized by skin hyperextensibility, tissue fragility, and generalized joint hypermobility. In addition to these commonly recognized phenotypes, recent studies have notably highlighted variable ophthalmic features in EDS. In this review, we comprehensively gather and discuss the ocular manifestations of EDS and its thirteen subtypes in the clinical setting.</p>