AUTHOR=Veličković Jelena , Vukičević Tatjana Adžić , Spurnić Aleksandra Radovanović , Lazić Igor , Popović Bojana , Bogdanović Ivan , Raičević Savo , Marić Dragana , Berisavac Ivana 

TITLE=Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.973817

DOI=10.3389/fmed.2022.973817

ISSN=2296-858X

ABSTRACT=<p>Coronavirus disease (COVID-19) in immunocompromised patients represents a major challenge for diagnostics, surveillance, and treatment. Some individuals remain SARS-CoV-2 PCR-positive for a prolonged period. The clinical and epidemiological significance of this phenomenon is not well understood. We report a case of a patient with a history of systemic lupus erythematosus (SLE) who has been persistently SARS-CoV-2 PCR positive for 9 months, with multiple thromboembolic complications, and development of nocardial brain abscess successfully treated with surgery and antibiotics.</p>