AUTHOR=Shi Fang-e , Chen Mei-fang , Li Yong-jie , Dong Gui-ying , Zhu Ji-hong 

TITLE=Campylobacter jejuni-Associated Hemophagocytic Lymphohistiocytosis and Guillain-Barre Syndrome: A Case Report

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.895923

DOI=10.3389/fmed.2022.895923

ISSN=2296-858X

ABSTRACT=<p><italic>Campylobacter jejuni</italic> (<italic>C. jejuni</italic>), a Gram-negative bacterium, belongs to microaerobic bacteria. We reported a 21-year-old male patient diagnosed with hemophagocytic lymphohistiocytosis (HLH) due to <italic>C. jejuni</italic> infection, who presented with multiple clinical manifestations of peripheral nerve injury, such as ophthalmoplegia, facial paralysis, and urinary retention during the treatment. Electromyography showed neurogenic injury and the final diagnosis was Guillain-Barre Syndrome (GBS). After treatment of dexamethasone combined with immunoglobulin, the patient was discharged from the hospital with partial recovery of neurological symptoms.</p>