AUTHOR=Bandeira Matilde , Di Cianni Federica , Marinello Diana , Arnaud Laurent , Cannizzo Sara , Carta Claudio , Cornet Alain , Barril Sara M. , Bulina Inita , Ferraris Alessandro , Fonseca João , Gaglioti Andrea , Limper Marteen , Lorenzoni Valentina , Majnik Judith , Matucci-Cerinic Marco , Palla Ilaria , Rednic Simona , Schneider Matthias , Smith Vanessa , Sulli Alberto , Søndergaard Klaus , Ticciati Simone , Tincani Angela , Turchetti Giuseppe , Talarico Rosaria , Cutolo Maurizio , Mosca Marta , Taruscio Domenica TITLE=An overlook on the current registries for rare and complex connective tissue diseases and the future scenario of TogethERN ReCONNET JOURNAL=Frontiers in Medicine VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.889997 DOI=10.3389/fmed.2022.889997 ISSN=2296-858X ABSTRACT=Background

Patient registries play a crucial role in supporting clinical practice, healthcare planning and medical research, offering a real-world picture on rare and complex connective tissue diseases (rCTDs). ERN ReCONNET launched the first European Registry Infrastructure with the aim to plan, upgrade and link registries for rCTDs, with the final goal to promote a harmonized data collection approach all over Europe for rCTDs.

Methods

An online survey addressed to healthcare professionals and patients' representatives active in the field of rCTDs was integrated by an extensive database search in order to build a mapping of existing registries for rCTDs.

Findings

A total of 140 registries were found, 38 of which include multiple diseases. No disease-specific registry was identified for relapsing polychondritis, mixed connective tissue disease and undifferentiated connective tissue disease.

Discussion

This overview on the existing registries for rCTDs provides a useful starting point to identify the gaps and the strengths of registries on the coverage of rCTDs, and to develop a common data set and data collection approach for the establishment of the TogethERN ReCONNET Infrastructure.