AUTHOR=Piquin Gwendoline , Chapron Thibaut , Abdelmassih Youssef , Martin Gilles , Edelson Catherine , Caputo Georges , Metge Florence 

TITLE=Coats disease in female population: A comparison of clinical presentation and outcomes

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.879110

DOI=10.3389/fmed.2022.879110

ISSN=2296-858X

ABSTRACT=<sec><title>Purpose</title><p>To compare clinical characteristics at presentation and outcomes of Coats disease between females and males.</p></sec><sec><title>Methods</title><p>In this retrospective, consecutive case series we included all children diagnosed with Coats disease in a single tertiary referral center. Initial clinical presentation, treatment and outcomes were collected.</p></sec><sec><title>Results</title><p>A total of 158 children were included, of whom 29 (18.3%) were females and 11 (6.9%) had bilateral involvement. Age at diagnosis and disease stage were similar between females and males. Females had more bilateral involvement (<italic>p</italic> &lt; 0.001) and tended to have a worse visual acuity at diagnosis (<italic>p</italic> = 0.05). At last follow-up, visual acuity and anatomical outcome after treatment were similar between genders.</p></sec><sec><title>Conclusion</title><p>Female patients with Coats disease had more bilateral involvement and tended to have worse visual acuity at presentation. Clinical presentation and outcomes seemed to be similar between genders.</p></sec>