AUTHOR=Shi Yu , Fan Yuchen , Chen Tao TITLE=Editorial: Acute-On-Chronic Liver Failure: Natural History, Mechanism, and Treatment JOURNAL=Frontiers in Medicine VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.867436 DOI=10.3389/fmed.2022.867436 ISSN=2296-858X