AUTHOR=Du Yali , Jin Chuang , Yin Shengjie , Wang Geng , Ma Qian , Li Yuancun , Chen Binyao , Wang Hongxi , Qiu Kunliang , Zhang Mingzhi 

TITLE=Comparison of Vault Measurements Using a Swept-Source OCT-Based Optical Biometer and Anterior Segment OCT

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.865719

DOI=10.3389/fmed.2022.865719

ISSN=2296-858X

ABSTRACT=<sec><title>Background</title><p>To newly describe the vault measurement by using a widely used swept-source OCT-based optical biometer (IOLMaster700) and accessd the accuracy of vault measurement.</p></sec><sec><title>Methods</title><p>This was a retrospective, cross-sectional study. All patients underwent implantable Collamer lens (ICL) implantation surgery without complications. IOLMaster700 and AS-OCT analyses were conducted for each eye on the same day in the same condition. Measurements of anterior chamber depth (ACD), corneal-ICL (C-ICL), and vault values were made and recorded. The repeatability of the IOL Master700 measurements was quantified based upon intraclass correlation coefficient (ICC) values. Correlations between IOL Master700 and AS-OCT measurements made with these different analytical approaches were assessed. The agreement of instruments was evaluated using Bland-Altman plots.</p></sec><sec><title>Results</title><p>The IOLMaster700 instrument yielded highly reliable measurements of vault, C-ICL, and ACD (<italic>ICC</italic> = 0.996, 0.995, 0.995, respectively). Vault, C-ICL and ACD values as measured using the IOLMaster700, was slightly smaller than that measured via AS-OCT, but these differences were not significant (<italic>p</italic> = 0.652<italic>, p</italic> = 0.121 and <italic>p</italic> = 0.091, respectively). The vault, C-ICL, and ACD measurements by these two instruments were strongly correlated (<italic>r</italic> = 0.971, <italic>r</italic> = 0.944, and <italic>r</italic> = 0.963, respectively; all <italic>p</italic> &lt; 0.001). The 95% limits of agreement for vault, C-ICL, and ACD measurements between the two devices were−0.08 to 0.08 mm,−0.14 to 0.11 mm, and−0.13 to 0.10 mm, respectively.</p></sec><sec><title>Conclusions</title><p>The IOLMasrer700 can measure implanted ICL vault with a high degree of accuracy and repeatability. Good correlations and agreement were observed between IOLMaster700 and AS-OCT in measuring vault, C-ICL, and ACD measurements.</p></sec>