AUTHOR=AlRyalat Saif Aldeen , Ertel Monica K. , Seibold Leonard K. , Kahook Malik Y. TITLE=Designs and Methodologies Used in Landmark Clinical Trials of Glaucoma: Implications for Future Big Data Mining and Actionable Disease Treatment JOURNAL=Frontiers in Medicine VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.818568 DOI=10.3389/fmed.2022.818568 ISSN=2296-858X