AUTHOR=Sampsonas Fotios , Karamouzos Vasileios , Karampitsakos Theodoros , Papaioannou Ourania , Katsaras Matthaios , Lagadinou Maria , Zarkadi Eirini , Malakounidou Elli , Velissaris Dimitrios , Stratakos Grigorios , Tzouvelekis Argyrios 

TITLE=High-Flow vs. Low-Flow Nasal Cannula in Reducing Hypoxemic Events During Bronchoscopic Procedures: A Systematic Review and Meta-Analysis

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.815799

DOI=10.3389/fmed.2022.815799

ISSN=2296-858X

ABSTRACT=<sec><title>Introduction</title><p>High-flow nasal cannula (HFNC) oxygenation method has been proven to be successful in oxygenation of patients with respiratory failure and has exhibited clinical superiority compared to low-flow nasal cannula (LFNC).</p></sec><sec><title>Methods</title><p>We performed a systematic review and meta-analysis to evaluate the potential favorable impact of HFNC oxygenation during bronchoscopy and related procedures like endobronchial ultrasound-transbronchial needle aspiration. Only randomized control trials (RCTs) were included in the meta-analysis.</p></sec><sec><title>Results</title><p>Six randomized control trials with 1,170 patients were included in this meta-analysis. Patients who underwent bronchoscopy with the use of high-flow nasal cannula experienced less hypoxemic events/desaturations, less procedural interruptions and pneumothoraxes compared to patients under low-flow nasal cannula treatment. This beneficial effect of HFNC in hypoxemic events was persistent 10 min after the end of procedure.</p></sec><sec><title>Conclusion</title><p>The high-flow nasal cannula (HFNC) oxygenation method could reduce hypoxemic events and related peri- and post-bronchoscopic complications.</p></sec>