AUTHOR=Ruan Xiaoting , Yang GuangYao , Xia Zhaoxia , Zhang Jiaqing , Gu Xiaoxun , Tan Yuan , Liu Zhenzhen , Luo Lixia 

TITLE=Agreement of Anterior Segment Parameter Measurements With CASIA 2 and IOLMaster 700

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2022

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.777443

DOI=10.3389/fmed.2022.777443

ISSN=2296-858X

ABSTRACT=<sec><title>Purpose</title><p>To compare the difference and agreement in central corneal thickness (CCT), keratometry (K), anterior chamber depth (ACD), aqueous depth (AQD), and lens thickness (LT) measured with CASIA 2 and IOLMaster 700 in patients with cataract.</p></sec><sec><title>Methods</title><p>A total of 81 patients with cataract (81 eyes) scheduled for phacoemulsification were prospectively collected from March to May, 2020 in the cataract department of Zhongshan Ophthalmic Center, Sun Yat-sen University, including 43 males and 38 females with age of 61.5 ± 10.6 years. CCT, anterior K<sub>f</sub>, anterior K<sub>s</sub>, real K<sub>f</sub>, real K<sub>s</sub>, ACD, AQD, and LT were measured with CASIA 2 and IOLMaster 700. Paired <italic>t</italic>-test, intraclass correlation coefficients (ICCs), 95% limit of agreement (95% LoA), and Bland-Altman plots were performed and used to analyze the difference and agreement between the two devices.</p></sec><sec><title>Results</title><p>There was no statistically significant difference in anterior K measurement with the CASIA 2 (44.3 ± 1.66 mm) and IOLMaster 700 (44.31 ± 1.67 mm, <italic>P</italic> = 0.483). Differences among the CCT, anterior K<sub>f</sub>, real K<sub>f</sub>, real K<sub>s</sub>, ACD, AQD, and LT measured by the two instruments were statistically significant (<italic>P</italic> &lt; 0.001). The ICCs of CCT, anterior K<sub>f</sub>, anterior K<sub>s</sub>, real K<sub>f</sub>, real K<sub>s</sub>, ACD, AQD, and LT measurements between the two devices were 0.892, 0.991, 0.991, 0.827, 0.817, 0.937, 0.926, and 0.997, respectively. The 95% LoA between CASIA 2 and IOLMaster 700 was −30.06 to 0.43 μm for CCT, −0.3 to 0.48 D for anterior Kf, −0.46 to −0.43 D for anterior Ks, −1.49 to −0.49 D for real Kf, −1.62 to −0.49 D for Real Ks, −0.03 to 0.24 mm for ACD, 0.04 to 0.25 mm for AQD, and −0.06 to 0.09 mm for LT.</p></sec><sec><title>Conclusion</title><p>Anterior K<sub>f</sub>, anterior K<sub>s</sub>, ACD, AQD, and LT have excellent agreement between the two devices. CCT, real K<sub>f</sub>, and real K<sub>s</sub> have moderate agreement between the two devices. It is recommended to use anterior K<sub>f</sub>, anterior Ks, ACD, AQD, and LT interchangeably between CASIA 2 and IOLMaster 700.</p></sec>