AUTHOR=Albertsson Per , Bäck Tom , Bergmark Karin , Hallqvist Andreas , Johansson Mia , Aneheim Emma , Lindegren Sture , Timperanza Chiara , Smerud Knut , Palm Stig 

TITLE=Astatine-211 based radionuclide therapy: Current clinical trial landscape

JOURNAL=Frontiers in Medicine

VOLUME=9

YEAR=2023

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.1076210

DOI=10.3389/fmed.2022.1076210

ISSN=2296-858X

ABSTRACT=<p>Astatine-211 (<sup>211</sup>At) has physical properties that make it one of the top candidates for use as a radiation source for alpha particle-based radionuclide therapy, also referred to as targeted alpha therapy (TAT). Here, we summarize the main results of the completed clinical trials, further describe ongoing trials, and discuss future prospects.</p>