AUTHOR=Oliveira Rudolf K. F. , Nyasulu Peter S. , Iqbal Adeel Ahmed , Hamdan Gul Muhammad , Ferreira Eloara V. M. , Leclair John William , Htun Zin Mar , Howard Luke S. , Mocumbi Ana O. , Bryant Andrew J. , Tamuzi Jacques L. , Avdeev Sergey , Petrosillo Nicola , Hassan Ahmed , Butrous Ghazwan , de Jesus Perez Vinicio TITLE=Cardiopulmonary disease as sequelae of long-term COVID-19: Current perspectives and challenges JOURNAL=Frontiers in Medicine VOLUME=9 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.1041236 DOI=10.3389/fmed.2022.1041236 ISSN=2296-858X ABSTRACT=

COVID-19 infection primarily targets the lungs, which in severe cases progresses to cytokine storm, acute respiratory distress syndrome, multiorgan dysfunction, and shock. Survivors are now presenting evidence of cardiopulmonary sequelae such as persistent right ventricular dysfunction, chronic thrombosis, lung fibrosis, and pulmonary hypertension. This review will summarize the current knowledge on long-term cardiopulmonary sequelae of COVID-19 and provide a framework for approaching the diagnosis and management of these entities. We will also identify research priorities to address areas of uncertainty and improve the quality of care provided to these patients.