AUTHOR=Fiore Vito , Beretta Rosalba , De Vito Andrea , Barac Aleksandra , Maida Ivana , Joeseph Kelvin David David , Piu Claudia , Lai Vincenzo , Madeddu Giordano , Rubino Salvatore , Stevanovic Goran , Korica Stefan , Babudieri Sergio TITLE=Emerging Clinical Features of COVID-19 Related Pancreatitis: Case Reports and Review of the Literature JOURNAL=Frontiers in Medicine VOLUME=8 YEAR=2022 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.779118 DOI=10.3389/fmed.2021.779118 ISSN=2296-858X ABSTRACT=Introduction

SARS-CoV-2 is fundamentally a respiratory pathogen with a wide spectrum of symptoms. The COVID-19 related pancreatitis is less considered than other clinical features. The purpose is to describe two cases of pancreatitis associated with COVID-19.

Methodology

Patients' demographics, clinical features, laboratory, and instrumental findings were collected.

Results

Two patients admitted to the hospital were diagnosed with COVID-19 and severe acute pancreatitis, according to the Atlanta criteria. Other causes of acute pancreatitis were excluded. Treatment included broad-spectrum antibiotics, proton pump inhibitors, and low molecular weight heparin. Steroids, oxygen, antifungal treatment, and pain killers were administered when appropriate. Both patients were asymptomatic, with normal vital parameters and blood exams, and were discharged in a good condition.

Conclusion

It is recommendable to include lipase and amylase on laboratory routine tests in order to evaluate the need for the abdominal CT-scan and specific therapy before hospital admission of the patients with COVID-19 related life-threatening acute pancreatitis.