AUTHOR=Bao Daorina , Tan Ying , Yu Xiaojuan , Wang Bingjie , Wang Hui , Xu Rong , Zhou Fude , Zhao Minghui 

TITLE=Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.759279

DOI=10.3389/fmed.2021.759279

ISSN=2296-858X

ABSTRACT=<p>In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.</p>