AUTHOR=Yao Zheng , Tian Weiliang , Xu Xin , Zhao Risheng , Zhao Yunzhao 

TITLE=Compared With a Nasointestinal Route, Pre-operative Enteral Nutrition via a Nasogastric Tube Reduced the Incidence of Acalculous Acute Cholecystitis After Definitive Surgery for Small Intestinal Fistula

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.721402

DOI=10.3389/fmed.2021.721402

ISSN=2296-858X

ABSTRACT=<p><bold>Purpose:</bold> This study aimed to investigate the difference in the efficacy of pre-operative enteral nutrition (EN) <italic>via</italic> a nasogastric tube (NGT) and pre-operative EN <italic>via</italic> a nasointestinal tube (NIT) in reducing the incidence of post-operative acalculous acute cholecystitis (AAC) after definitive surgery (DS) for small intestinal fistulas.</p><p><bold>Methods:</bold> Patients with a small intestinal fistula, who had a DS for the disease between January 2015 and March 2021, were enrolled in this study. They were divided into the NIT group and the NGT group based on the pre-operative routes of feeding they received. The clinical characteristics of the two groups were analyzed, and the incidences of post-operative AAC in the two groups were evaluated.</p><p><bold>Results:</bold> A total of 200 patients were enrolled in the study, 85 in the NGT group and 115 in the NIT group. Thirty-one patients developed post-operative AAC (8 in the NGT group and 23 in the NIT group). The incidence of post-operative AAC was 15.5%. EN <italic>via</italic> the NGT route was associated with a reduction in the incidence of post-operative AAC (adjusted HR = 0.359; 95% CI: 0.139–0.931; <italic>P</italic> = 0.035).</p><p><bold>Conclusion:</bold> Pre-operative EN <italic>via</italic> the NGT may reduce the incidence of post-operative AAC in patients who received a DS for small intestinal fistulas.</p>