AUTHOR=Xu Wen , Tan Ruoming , Huang Jie , Qin Shuai , Wu Jing , Qiu Yuzhen , Xie Simin , Xu Yan , Du Ying , Li Feng , Li Bailing , Li Yingchuan , Gao Yuan , Li Xin , Qu Hongping 

TITLE=Case Report: Respiratory Management With a 47-Day ECMO Support for a Critical Patient With COVID-19

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.714387

DOI=10.3389/fmed.2021.714387

ISSN=2296-858X

ABSTRACT=<p>This paper reports a complete case of severe acute respiratory distress syndrome (ARDS) caused by coronavirus disease 2019 (COVID-19), who presented with rapid deterioration of oxygenation during hospitalization despite escalating high-flow nasal cannulation to invasive mechanical ventilation. After inefficacy with lung-protective ventilation, positive end-expiratory pressure (PEEP) titration, prone position, we administered extracorporeal membrane oxygenation (ECMO) as a salvage respiratory support with ultra-protective ventilation for 47 days and finally discharged the patient home with a good quality of life with a Barthel Index Score of 100 after 76 days of hospitalization. The purpose of this paper is to provide a clinical reference for the management of ECMO and respiratory strategy of critical patients with COVID-19-related ARDS.</p>