AUTHOR=Zhang Shaomin , Xian Hong , Chen Yi , Liao Yue , Zhang Nan , Guo Xinyu , Yang Ming , Wu Jinhui 

TITLE=The Auxiliary Diagnostic Value of a Novel Wearable Electrocardiogram-Recording System for Arrhythmia Detection: Diagnostic Trial

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.685999

DOI=10.3389/fmed.2021.685999

ISSN=2296-858X

ABSTRACT=<p><bold>Background:</bold> AMAZFIT<sup>®</sup>, a novel wearable electrocardiogram (ECG)-recording system is used for the measurement, acquisition, and storage of single-lead cardiac waveforms for adults. The aim of the study was to evaluate the accuracy of AMAZFIT<sup>®</sup> for diagnosing arrhythmia in older patients.</p><p><bold>Methods:</bold> From May to December 2019, we recruited 291 elderly individuals with an average age of 78±10 years old, and 41.9% women. All cardiac waveforms were obtained from the AMAZFIT<sup>®</sup> which included limb and chest leads. Two trained technicians reviewed all ECG data to determine cardiac rhythm using standard diagnostic criteria. We evaluated the accuracy of AMAZFIT<sup>®</sup> for identifying arrhythmia by comparing the sensitivity, specificity, accuracy, positive predictive value (PPV), negative predictive value (NPV), and positive and negative likelihood ratios with those of a standard 12-lead ECG.</p><p><bold>Results:</bold> Of the 291 participants, 197 older adults had arrhythmias, including AF (<italic>n</italic> = 119), first-degree AVB (<italic>n</italic> = 28), PACs (<italic>n</italic> = 25), and PVCs (<italic>n</italic> = 28). Three of these participants had arrhythmias of AF and PVCs. Chest lead data from 100% and limb lead data from 4.7% of the participants were analyzed. An evaluation of AMAZFIT<sup>®</sup> for atrial fibrillation (AF) reported a sensitivity, specificity, PPV, NPV PLR, and negative likelihood ratio (NLR) of 93.28, 95.35, 93.28, 95.35, 20.06, and 0.07%, respectively. AMAZFIT<sup>®</sup> also demonstrated excellent sensitivity for premature atrial contractions (PACs) (84.00%) and premature ventricular contractions (PVCs) (89.29%). However, the device demonstrated a low sensitivity for first-degree atrioventricular block (32.14%).</p><p><bold>Conclusions:</bold> The AMAZFIT<sup>®</sup> showed significantly higher sensitivity and specificity for AF, PACs, and PVCs. This portable ECG-recording device based on an algorithm has a potential auxiliary diagnostic value for identifying arrhythmia compared with a standard 12-lead ECG device.</p>