AUTHOR=Gong Yuehua , Li Jianlin , Zhu Dongnan , Wang Songsong , Xu Yingchun , Li Yan , Wang Yanqing , Song Yan , Liu Wenjuan , Tian Yunlong 

TITLE=Case Report: Near-Fatal Intestinal Hemorrhage and Acute Acalculous Cholecystitis due to Vi-Negative and Fluoroquinolone-Insensitive Salmonella enterica Serovar Typhi Infection: A Rare Entity

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.666643

DOI=10.3389/fmed.2021.666643

ISSN=2296-858X

ABSTRACT=<p>Typhoid fever is usually a mild clinical disease. Typhoid fever with massive intestinal hemorrhage is rare in the antibiotic era. Acute acalculous cholecystitis (AAC) is also rare in adults. Here, we describe the first adult case of typhoid fever with both complications due to Vi-negative and fluoroquinolone-insensitive <italic>Salmonella enterica</italic> serovar Typhi (<italic>S</italic>. Typhi) infection. We aim to alert physicians to this rare condition.</p>