AUTHOR=Schifferli Alexandra , Cavalli Franco , Godeau Bertrand , Liebman Howard A. , Recher Mike , Imbach Paul , Kühne Thomas 

TITLE=Understanding Immune Thrombocytopenia: Looking Out of the Box

JOURNAL=Frontiers in Medicine

VOLUME=8

YEAR=2021

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2021.613192

DOI=10.3389/fmed.2021.613192

ISSN=2296-858X

ABSTRACT=<p>The pathogenesis of immune thrombocytopenia (ITP) is increasingly being elucidated, and its etiology is becoming more frequently identified, leading to a diagnostic shift from primary to secondary ITP. The overlap between autoimmunity, immunodeficiency, and cancer is evident, implying more interdisciplinarity in daily care. This mini-review is based on an expert meeting on ITP organized by the Intercontinental Cooperative ITP Study Group and presents the challenges of hematologists in understanding and investigating “out of the box” concepts associated with ITP.</p>