AUTHOR=Rotta Denise , Fassio Angelo , Rossini Maurizio , Giollo Alessandro , Viapiana Ombretta , Orsolini Giovanni , Bertoldo Eugenia , Gatti Davide , Adami Giovanni 

TITLE=Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment

JOURNAL=Frontiers in Medicine

VOLUME=7

YEAR=2020

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2020.613720

DOI=10.3389/fmed.2020.613720

ISSN=2296-858X

ABSTRACT=<p>Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective.</p>