AUTHOR=Górski Andrzej , Jończyk-Matysiak Ewa , Międzybrodzki Ryszard , Weber-Dąbrowska Beata , Łusiak-Szelachowska Marzanna , Bagińska Natalia , Borysowski Jan , Łobocka Małgorzata B. , Węgrzyn Alicja , Węgrzyn Grzegorz TITLE=Phage Therapy: Beyond Antibacterial Action JOURNAL=Frontiers in Medicine VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00146 DOI=10.3389/fmed.2018.00146 ISSN=2296-858X ABSTRACT=

Until recently, phages were considered as mere “bacteria eaters” with potential for use in combating antimicrobial resistance. The real value of phage therapy assessed according to the standards of evidence-based medicine awaits confirmation by clinical trials. However, the progress in research on phage biology has shed more light on the significance of phages. Accumulating data indicate that phages may also interact with eukaryotic cells. How such interactions could be translated into advances in medicine (especially novel means of therapy) is discussed herein.