AUTHOR=Vonend Oliver , Martin Ole , Rump Lars C. , Kroepil Patrick , Stegbauer Johannes TITLE=Erythrocyte Salt Sedimentation Assay Does Not Predict Response to Renal Denervation JOURNAL=Frontiers in Medicine VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00051 DOI=10.3389/fmed.2018.00051 ISSN=2296-858X ABSTRACT=
Renal denervation (RDN) has recently been shown to be effective in patients without antihypertensive medication. However, about 30% of patients do not respond to RDN, and therefore, there exists a need to find predictors of response. Individuals are either salt-sensitive (SS) or non-salt-sensitive (NSS) in terms of their blood pressure (BP) regulation. The sympathetic nervous system can influence water and salt handling. RDN reduces sympathetic drive and has an impact on salt excretion. The present study was conducted to test the influence of salt sensitivity in terms of the BP reducing effect after RDN procedure. Salt sensitivity was estimated using the