AUTHOR=Fot Evgenia V. , Izotova Natalia N. , Yudina Anjelika S. , Smetkin Aleksei A. , Kuzkov Vsevolod V. , Kirov Mikhail Y. 

TITLE=The Predictive Value of Integrated Pulmonary Index after Off-Pump Coronary Artery Bypass Grafting: A Prospective Observational Study

JOURNAL=Frontiers in Medicine

VOLUME=4

YEAR=2017

URL=https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2017.00132

DOI=10.3389/fmed.2017.00132

ISSN=2296-858X

ABSTRACT=<sec id="ST1"><title>Background</title><p>The early warning scores may increase the safety of perioperative period. The objective of this study was to assess the diagnostic and predictive role of Integrated Pulmonary Index (IPI) after off-pump coronary artery bypass grafting (OPCAB).</p></sec><sec id="ST2"><title>Materials and Methods</title><p>Forty adult patients undergoing elective OPCAB were enrolled into a single-center prospective observational study. We assessed respiratory function using IPI that includes oxygen saturation, end-tidal CO<sub>2</sub>, respiratory rate, and pulse rate. In addition, we evaluated blood gas analyses and hemodynamics, including ECG, invasive arterial pressure, and cardiac index. The measurements were performed after transfer to the intensive care unit, after spontaneous breathing trial and at 2, 6, 12, and 18 h after extubation.</p></sec><sec id="ST3"><title>Results and Discussion</title><p>The value of IPI registered during respiratory support correlated weakly with cardiac index (rho = 0.4; <italic>p</italic> = 0.04) and ScvO<sub>2</sub> (rho = 0.4, <italic>p</italic> = 0.02). After extubation, IPI values decreased significantly, achieving a minimum by 18 h. The IPI value ≤9 at 6 h after extubation was a predictor of complicated early postoperative period (AUC = 0.71; <italic>p</italic> = 0.04) observed in 13 patients.</p></sec><sec id="ST4"><title>Conclusion</title><p>In off-pump coronary surgery, the IPI decreases significantly after tracheal extubation and may predict postoperative complications.</p></sec>