94% of researchers rate our articles as excellent or good
Learn more about the work of our research integrity team to safeguard the quality of each article we publish.
Find out more
REVIEW article
Front. Mater.
Sec. Biomaterials and Bio-Inspired Materials
Volume 12 - 2025 | doi: 10.3389/fmats.2025.1530524
Impact of Hydrogel-Based Airway Management Strategies on Ventilator-Associated Pneumonia: Clinical Applications and Future Directions
Provisionally accepted
Yong Xu 1
Baisong Zhao 2*- 1 First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning Province, China
- 2 Zhujiang Hospital, Southern Medical University, Guangzhou, China
This review discusses the current applications of hydrogels in the management of airway lung injury and ventilator-associated pneumonia (VAP), with a particular focus on their potential impact in clinical practice. Research indicates that hydrogel technology can not only enhance airway management and promote lung tissue repair but also significantly reduce the risk of infection. For instance, clinical trials have shown that hydrogel-coated endotracheal tubes are effective at reducing the incidence of VAP, with related data indicating a reduction of up to 30%. Furthermore, we analyze the limitations of current research and propose directions for the future development of hydrogel-based therapies in this important field of respiratory medicine.
Keywords: Biomaterials, Hydrogels, Airway Lung Injury, Ventilator-associated, Pneumonia
Received: 19 Nov 2024; Accepted: 17 Feb 2025.
Copyright: © 2025 Xu and Zhao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Baisong Zhao, Zhujiang Hospital, Southern Medical University, Guangzhou, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.