AUTHOR=Shortell Matthew P. , Althomali Marwan A. M. , Wille Marie-Luise , Langton Christian M. 

TITLE=Combining Ultrasound Pulse-Echo and Transmission Computed Tomography for Quantitative Imaging the Cortical Shell of Long-Bone Replicas

JOURNAL=Frontiers in Materials

VOLUME=4

YEAR=2017

URL=https://www.frontiersin.org/journals/materials/articles/10.3389/fmats.2017.00040

DOI=10.3389/fmats.2017.00040

ISSN=2296-8016

ABSTRACT=<p>We demonstrate a simple technique for quantitative ultrasound imaging of the cortical shell of long-bone replicas. Traditional ultrasound computed tomography instruments use the transmitted or reflected waves for separate reconstructions but suffer from strong refraction artifacts in highly heterogeneous samples such as bones in soft tissue. The technique described here simplifies the long bone to a two-component composite and uses both the transmitted and reflected waves for reconstructions, allowing the speed of sound and thickness of the cortical shell to be calculated accurately. The technique is simple to implement, computationally inexpensive, and sample positioning errors are minimal.</p>