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ORIGINAL RESEARCH article

Front. Mar. Sci.
Sec. Global Change and the Future Ocean
Volume 11 - 2024 | doi: 10.3389/fmars.2024.1492142

Pseudoalteromonas flavipulchra as a dual-functional probiotic for aquaculture: Enhancing microalgae growth and antagonizing Vibrio pathogens

Provisionally accepted
Minnan Wu Minnan Wu Yi-Jun Xu Yi-Jun Xu Meng-Meng Shao Meng-Meng Shao Zi-Yue Wang Zi-Yue Wang Jiayi Cao Jiayi Cao *Jilin Xu Jilin Xu *
  • Ningbo University, Ningbo, China

The final, formatted version of the article will be published soon.

    Vibrio disease is a prevalent bacterial infection in aquaculture, and using bacteria with antagonistic properties against Vibrio species as probiotics has emerged as a promising method for disease prevention. Additionally, low biomass productivity of microalgae feed remains a significant bottleneck in bivalve aquaculture. Therefore, it is essential to screen for bacteria that both enhance microalgae growth and inhibit Vibrio pathogens. In this work, we screened seven microalgae growth-promoting bacterial for their antibacterial activity against three Vibrio pathogens, i.e., Vibrio vulnificus, Vibrio parahaemolyticus and Vibrio cholerae, and found that Pseudoalteromonas flavipulchra exhibited antagonistic effects against all three tested Vibrio species. The extracellular products (ECP) of P. flavipulchra exhibited stable antibacterial activity, but it was lost after treatment with heat, alkali, or proteinase K. The proteinaceous material isolated from the ECP by precipitation with 90% saturated ammonium sulfate exhibited antibacterial activity in a concentration-dependent manner. According to these findings P. flavipulchra could be a promising dual-functional probiotic for aquaculture.

    Keywords: Microalgae growth-promoting bacteria, Pseudoalteromonas flavipulchra, Vibrio, Antibacterial activity, Antibacterial substance

    Received: 06 Sep 2024; Accepted: 21 Oct 2024.

    Copyright: © 2024 Wu, Xu, Shao, Wang, Cao and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Jiayi Cao, Ningbo University, Ningbo, China
    Jilin Xu, Ningbo University, Ningbo, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.