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ORIGINAL RESEARCH article
Front. Mar. Sci.
Sec. Aquatic Physiology
Volume 11 - 2024 |
doi: 10.3389/fmars.2024.1443484
Effects of cadmium on the growth, muscle composition, digestion, gene expression of antioxidant and lipid metabolism in juvenile tilapia (Oreochromis niloticus)
Provisionally accepted
Qin Zhang
Yi Xie
*
Rongxin Qin
*
Enhao Huang
*
Ziqi Zhang
*
Jiang Zhou
*
Dongsheng Liu
*
Liuqing Meng
*
Yongqiang Liu
*
Tong Tong
*- Guangxi Minzu University, Guangxi, China
Cadmium could induce various degrees of harm to aquatic organisms. A 30-day feeding trial was conducted to investigate the effects of cadmium on growth, muscle composition, digestive enzyme activity, gene expression of antioxidants and lipid metabolism in juvenile genetic improvement of farmed tilapia (GIFT, Oreochromis niloticus, Initial weight: 21.36 ± 0.24 g). Four cadmium concentrations of aquaculture water were designed: 0, 0.2, 0.4, and 0.6 mg/L Cd 2+ . The main results are as follows:Compared with the control group (0 mg/L Cd 2+ ), the weight gain rate (WGR), specific growth rate (SGR), daily growth index (DGI), and spleen index (SI) of juvenile GIFT under cadmium stress were significantly decreased (p < 0.05). The contents of crude protein and crude lipid in muscle were significantly decreased (p < 0.05), and the ash was significantly increased (p < 0.05). The activities of trypsin, lipase, and α-amylase in the intestinal were significantly decreased (p < 0.05). The relative expression levels of carnitine palmityl transferase 1 (cpt-1), peroxisome proliferator-activated receptor α (pparα), pparγ, hormone-sensitive lipase (hsl), lipoprotein lipase (lpl), malate dehydrogenase (mdh), leptin (lep), fatty acid synthetase (fas), cholesterol response element binding protein 1 (srebp1), squalene cyclooxygenase (sqle), and stearoyl-CoA desaturase (scd) genes in liver were significantly decreased (p < 0.05). The relative expression levels of catalase (cat), superoxide dismutase (sod), glutathione Stransferase (gst), and glutathione peroxidase (gsh-px) genes in the liver were significantly decreased (p < 0.05). In conclusion, exposure to cadmium stress could impact growth, muscle composition, digestive enzyme activity, gene expression of antioxidant and lipid metabolism in juvenile GIFT.
Keywords: Growth, antioxidant, Lipid Metabolism, Cadmium, Tilapia
Received: 04 Jun 2024; Accepted: 03 Jul 2024.
Copyright: © 2024 Zhang, Xie, Qin, Huang, Zhang, Zhou, Liu, Meng, Liu and Tong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yi Xie, Guangxi Minzu University, Guangxi, China
Rongxin Qin, Guangxi Minzu University, Guangxi, China
Enhao Huang, Guangxi Minzu University, Guangxi, China
Ziqi Zhang, Guangxi Minzu University, Guangxi, China
Jiang Zhou, Guangxi Minzu University, Guangxi, China
Dongsheng Liu, Guangxi Minzu University, Guangxi, China
Liuqing Meng, Guangxi Minzu University, Guangxi, China
Yongqiang Liu, Guangxi Minzu University, Guangxi, China
Tong Tong, Guangxi Minzu University, Guangxi, China
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