AUTHOR=Lou Fangrui , Wang Li , Wang Zhiyang , Wang Lei , Zhao Linlin , Zhou Qingjie , Lu Zhichuang , Tang Yongzheng 

TITLE=Full-Length Transcriptome of the Whale Shark (Rhincodon typus) Facilitates the Genome Information

JOURNAL=Frontiers in Marine Science

VOLUME=8

YEAR=2022

URL=https://www.frontiersin.org/journals/marine-science/articles/10.3389/fmars.2021.821253

DOI=10.3389/fmars.2021.821253

ISSN=2296-7745

ABSTRACT=<p><italic>Rhincodon typus</italic> is a keystone and indicator species in marine ecosystems. Meanwhile, <italic>R. typus</italic> has been listed on the IUCN red list of vulnerable species. Here we used ONT platform to determine the full-length (FL) transcriptome of <italic>R. typus</italic> and obtained 14,930 FL transcripts. Among all FL transcripts, 14,915 transcripts were covered 11,892 genetic loci and 1,642 novel genetic loci were further found. Meanwhile, we identified 714 novel transcripts by compared FL transcripts with the <italic>R. typus</italic> genome. Based on FL transcripts, we also predicted the distribution patterns of ASs, LncRNAs, polyAs, CDSs and methylation sites on FL transcriptome of <italic>R. typus</italic>. Furthermore, a total of 31,021 (97.86%) CDSs can obtained annotation information. Overall, our work firstly provided the FL transcriptome and these sequences complete the annotated <italic>R. typus</italic> genome information. Furthermore, these information are a potential resource to study biological processes of <italic>R. typus</italic>.</p>