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ORIGINAL RESEARCH article

Front. Malar.

Sec. Vectors

Volume 3 - 2025 | doi: 10.3389/fmala.2025.1489687

This article is part of the Research Topic Women in Malaria Research View all 14 articles

Adult-capture assays as a tool to measure insecticide resistance in Anopheles malaria vectors: a modeling comparison with larval-capture assays

Provisionally accepted
  • 1 Deparment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States
  • 2 Center for Communicable Disease Dynamics, Harvard T.H. Chan School of Public Health, Boston, MA, United States
  • 3 Department of Mathematics, Virginia Tech Center for the Mathematics of Biosystems, Center for Emerging, Zoonotic and Arthropod-borne Pathogens, Blacksburg, VA, United States

The final, formatted version of the article will be published soon.

    Insecticides used to target the mosquito vectors of malaria are a cornerstone of global malaria control and have been credited with most of the reductions in malaria prevalence in the past 20 years. However, resistance to these insecticides has become widespread in many parts of sub-Saharan Africa. Monitoring insecticide resistance over time and in different settings is an important component of surveillance for malaria control programs. In this study, we use modeling to investigate the potential for adult-capture samples rather than the standard larval samples for use in insecticide resistance assays used to measure the presence of insecticide resistance. The ability to use adult-capture assays, which can be done more quickly, in a wider set of locations, and in the absence of an insectary, has the potential to improve the monitoring of insecticide resistance. We are submitting specifically to the Women in Malaria Research" series, as the authors of this manuscript are women who conduct research on malaria.

    Keywords: Malaria, Anopheles, Insecticide Resistance, vector control, resistance monitoring

    Received: 01 Sep 2024; Accepted: 25 Feb 2025.

    Copyright: © 2025 Holmdahl, Buckee and Childs. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Inga Holmdahl, Deparment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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