AUTHOR=Smaili Rachid , Ferjouchia Zahra , Elbachiri Soumaya , Bourkia Myriem 

TITLE=Ataxic sensory neuronopathy with isolated anti-Ro/SS-A antibody during pregnancy: a case report of adverse outcomes

JOURNAL=Frontiers in Lupus

VOLUME=2

YEAR=2024

URL=https://www.frontiersin.org/journals/lupus/articles/10.3389/flupu.2024.1461157

DOI=10.3389/flupu.2024.1461157

ISSN=2813-6934

ABSTRACT=<p>We present the rare case of a 33-year-old pregnant woman who developed severe ataxic sensory neuronopathy associated with isolated anti-Ro/SS-A antibodies without other features of Sjögren's syndrome. Her symptoms, which began with numbness and paresthesia, progressed to severe ataxia and sensory impairment, complicated by preeclampsia and intrauterine fetal death. Despite treatment with intravenous immunoglobulin, azathioprine, and steroids, she remains disabled. This case raises awareness for anti-Ro/SS-A antibodies in pregnant women and underscores the importance of early intervention and a multidisciplinary approach to prevent severe neurological disability.</p>