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CASE REPORT article

Front. Lupus
Sec. Reproductive Issues in Lupus
Volume 2 - 2024 | doi: 10.3389/flupu.2024.1461157
This article is part of the Research Topic Reproductive Issues In Lupus, Antiphospholipid Syndrome And Other Autoimmune Rheumatic Diseases: Highlights From RheumaPreg2023 View all 4 articles

Ataxic Sensory Neuronopathy with Isolated anti-Ro/SS-A Antibody During Pregnancy: A Case Report of Adverse Outcomes

Provisionally accepted
Rachid Smaili Rachid Smaili 1*Zahra Ferjouchia Zahra Ferjouchia 2Soumaya Elbachiri Soumaya Elbachiri 1Myriem Bourkia Myriem Bourkia 1
  • 1 Internal Medicine and Clinical Immunology, University Hospital MOHAMMED VI, Tangier, Morocco
  • 2 Neurology departement of University Hospital MOHAMMED VI, Tangier, Morocco

The final, formatted version of the article will be published soon.

    We present the rare case of a 33-year-old pregnant woman who developed severe ataxic sensory neuronopathy associated with isolated anti-Ro/SS-A antibodies without other features of Sjögren's syndrome. Her symptoms, which began with numbness and paresthesia, progressed to severe ataxia and sensory impairment, complicated by preeclampsia and intrauterine fetal death. Despite treatment with intravenous immunoglobulin, azathioprine, and steroids, she remains disabled. This case raises awareness for anti-Ro/SS-A antibodies in pregnant women and underscores the importance of early intervention and a multidisciplinary approach to prevent severe neurological disability.

    Keywords: Sensory neuronopathy1, Pregnancy2, anti Ro/SS-A antibodies3, Sjogren's syndrome 4, fetal death5

    Received: 07 Jul 2024; Accepted: 27 Aug 2024.

    Copyright: © 2024 Smaili, Ferjouchia, Elbachiri and Bourkia. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Rachid Smaili, Internal Medicine and Clinical Immunology, University Hospital MOHAMMED VI, Tangier, Morocco

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