AUTHOR=Huang Kerui , Liu Ying , Perrimon Norbert TITLE=Roles of Insect Oenocytes in Physiology and Their Relevance to Human Metabolic Diseases JOURNAL=Frontiers in Insect Science VOLUME=2 YEAR=2022 URL=https://www.frontiersin.org/journals/insect-science/articles/10.3389/finsc.2022.859847 DOI=10.3389/finsc.2022.859847 ISSN=2673-8600 ABSTRACT=
Oenocytes are large secretory cells present in the abdomen of insects known to synthesize very-long-chain fatty acids to produce hydrocarbons and pheromones that mediate courtship behavior in adult flies. In recent years, oenocytes have been implicated in the regulation of energy metabolism. These hepatocyte-like cells accumulate lipid droplets under starvation and can non-autonomously regulate tracheal waterproofing and adipocyte lipid composition. Here, we summarize evidence, mostly from